Unable to load your collection due to an error, Unable to load your delegates due to an error. They later ossify in a craniocaudal direction. A bronchus, which is also known as a main or primary bronchus, represents the airway in the respiratory tract that conducts air into the lungs. Revisions: 27. Alveolar ducts are tubular portions with respiratory surfaces from which the alveolar sacs bud. The sternal angle marks the location of the: Bifurcation of the trachea Second costal cartilage O . The angle decreases by 10 on expiration. The tracheal cartilages are composed of hyaline cartilage and interconnected by fibroelastic tissue. Instant Anatomy. Other anatomic structures are present at the general level of this plane. Bifurcation of trachea at sternal angle What are the 3 components of the middle. The trachea divides into the left and right main bronchus, which is known as the tracheal bifurcation, at the level of the sternal angle and of the fifth thoracic vertebra (or up to two vertebrae higher or lower, depending on lung volume changes due to breathing). Contributed by William Gossman Collection. It overlies the aortic arch on the left and the superior vena cava on the right. An anatomic variant of chest wall musculature. U.S. National Cancer Institute. and grab your free ultimate anatomy study guide! The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). StatPearls Publishing, Treasure Island (FL). Some patients are often described as pink puffers due to their efforts required to breathe in enough air and devices known as asthma puffers (or more commonly, inhalers) can help alleviate asthma. Your email address will not be published. Aug 8, Anatomy, Head and Neck, Cervical, Respiratory, Larynx, and Cricoarytenoid. which is an imaginary plane passing from the sternal angle anteriorly to the lower border of the body of the 4th thoracic vertebra posteriorly; laterally by the pleurae; Chen JT, Putman CE, Hedlund LW, Dahmash NS, Roberts L. Widening of the subcarinal angle by pericardial effusion. -, De Rose V, Molloy K, Gohy S, Pilette C, Greene CM. Segmentum apicoposterius pulmonis sinistri. Evidence-Based Medicine and Statistics for Medical Exams, Spinal root of accessory nerve crosses transverse process of atlas. Federal government websites often end in .gov or .mil. Common causes of congenital stridor in infants. The intercostal space superior and inferior to the angle of Louisis spanned by a triple layer of muscle. Its main function is to transport oxygenated air from the upper respiratory tract towards the alveoli for gas exchange. The airway, or respiratory tract, describes the organs of the respiratory tract that allow airflow during ventilation. The sternal angle is this angle formed between the manubrium of the sternum and the body of the sternum. The sternum develops at the same time as the rest of the ribcage from mesenchymal bands or bars which develop chondritic tissues as they move ventrally and medially forming cartilaginous shapes of the adult bones. Aug 8, Anatomy, Head and Neck, Larynx Vocal Cords. Fig 1 - Overview of the tracheobronchial tree. Epub 2020 Mar 26. At the time the article was last revised Ian Bickle had no recorded disclosures. They contain surfactant producing type II pneumocytes and Clara cells. Because of the strength of the bone, a mechanical saw is required to access the chest cavity. It performs generic functions of the skeletal tissues; protection, mechanical leverage for movement, and support for other organs. It is mandatory to procure user consent prior to running these cookies on your website. The Angle of Louis. [2], The carina occurs at the lower end of the trachea - usually at the level of the 4th to 5th thoracic vertebra. Need a refresher on the basic anatomy of the respiratory system before diving into all things bronchi related? Albuterol is a commonly used short acting 2-adrenergic receptor agonist that quickly allow for bronchodilation. The carina is the sagittally-oriented cartilaginous ridge at the bifurcation of the trachea and is an important reference point in chest imaging. The trachea also protects the respiratory tract via physical and immunological methods. Register now This is the most sensitive area of the trachea for triggering the cough reflex, and can be seen on bronchoscopy. -the head's position -adjacent organs with a connective tissue, the movement is very small (up to 1-2 cm) The length of the trachea is 10-12 cm and it is 1-2 cm longer in males -> 2 parts National Library of Medicine Last reviewed: October 25, 2022 Secondary bronchi will further subdivide into the tertiary bronchi, which are also called the segmental bronchi, each of which supplies a bronchopulmonary segment. Thus absolute measurements of the angle of tracheal bifurcation (IBA/SCA) are of little diagnostic value and even grossly widened angles should not be interpreted as abnormal 1. Onoe R, Yamashiro T, Handa H, Azagami S, Matsuoka S, Inoue T, Miyazawa T, Mineshita M. Int J Chron Obstruct Pulmon Dis. Parasympathetic supply originates from the recurrent laryngeal nerves, branches of the vagus nerve. The next set of muscles, the internal intercostals, are also oriented in an oblique fashion, orthogonally to the external intercostals. The tracheal bifurcation is the point at which the trachea divides into, and is continuous with, the two main or principal bronchi. van der Merwe AE, Weston DA, Oostra RJ, Maat GJ. [2] The carina occurs at the lower end of the trachea - usually at the level of the 4th to 5th thoracic vertebra. Check for errors and try again. Also, the angle varies, sometimes by 20%, in serial radiographs. [1][2], The carina is a cartilaginous ridge separating the left and right main bronchi that is formed by the inferior-ward and posterior-ward prolongation of the inferior-most tracheal cartilage. The trachea is part of the conducting zone of the respiratory system. The site is secure. Aortic ach begins 8. Immature lungs of a preterm infant often fail to produce sufficient surfactant, which leads to respiratory problems. 95% of the patients have normal values between 40-80 . This is because the manubrium normally angles posteriorly on the body of the sternum, forming a raised feature referred to as the sternal angle. These variations are due to both abnormal angles of the sternal angle and to curvatures of the sternal body. Careers. Access over 1700 multiple choice questions. Ball M, Falkson SR, Adigun OO. American journal of roentgenology. The mean angle of tracheal bifurcation is 60 (+/- 10 ), i.e. 2017 Jun;10(2):188-192. doi: 10.21053/ceo.2016.00185. This is where the 2nd rib joins with the sternum. The sternum and manubrium are innervated by the intercostal nerves which arepart of the somatic nervous system. The trachea is normally easy to follow inferi-orly until it bifurcates into right and left main bronchi. Read more. Patients with chronic bronchitis often also suffer from chronic obstructive pulmonary disease (COPD), with common associations with smoking or long-term exposure to irritants. The trapped particles are then removed from the trachea via the mucociliary rejection current. If the wrong rib is counted, access to the internal chest organs can be difficult. Wani TM, Bissonnette B, Engelhardt T, Buchh B, Arnous H, AlGhamdi F, Tobias JD. Anatomy, Angle of Louis. There are 10 bronchopulmonary segments in the right lung (3 in the superior lobe, 2 in the middle lobe, 5 in the inferior lobe), and 8 segments in the left lung (4 in the upper lobe, 4 in the lower lobe). The mean angle of tracheal bifurcation is 60 (+/- 10 ), i.e. Question: Which of the following takes place at the sternal angle (MACA) Arch of the aorta Esophgus enters the anterior mediastinum Thoracic duct crosses left and posterior to the esophagus Bifurcation of the trachea Articulation of rib 2 . At the time the article was created Gabrielle Edney had no recorded disclosures. These cookies do not store any personal information. Arterial supply comes from the tracheal branches of the inferior thyroid artery, while venous drainage is viathe brachiocephalic, azygos and accessory hemiazygos veins. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Would you like email updates of new search results? Brichon PY, Wihlm JM. (2000). In such cases, a tracheal tube or airway stents are used to bypass the obstruction and maintain the trachea open. document. The bronchioles consist of first the terminal bronchioles, then the respiratory bronchioles, and finally the alveolar sacs (which allow for gas exchange). Bifurcation of trachea. Main bronchi: There are two supplying ventilation to each lung. Each main bronchus divides into increasingly smaller intrapulmonary bronchi that supply the lungs; The trachea is related to many anatomical structures as it travels between the neck and mediastinum. Indian J Anaesth. Alveolar sacs are the blind-ended spaces from which the alveoli clusters are formed and to where they connect. The bronchi derive innervation from pulmonary branches of the vagus nerve (CN X). Computed tomography-based bronchial tree three-dimensional reconstruction and airway resistance evaluation in adolescent idiopathic scoliosis. Last reviewed: December 05, 2022 Necessary cookies are absolutely essential for the website to function properly. It marks the point at which the costal cartilages of the second rib articulate with the sternum. It is roughly at the level of the bifurcation of the pulmonary trunk. A bronchopulmonary segment is a division of the lung that is separated from the rest of the lung by a septum of connective tissue, which is an advantage during surgery since a bronchopulmonary segment can be removed without affects other nearby segments. This is particularly useful when counting ribs to identify landmarks as rib one is often impalpable. The pericardium extends from just superior to the angle of Louis to the level of the xiphisternal joint. The sternal angle is a crucial clinical marker for locating numerous other anatomical . eCollection 2018. The optimal location for auscultation of the aortic valve is generally the right second intercostal space, whereas the optimal location for auscultation of the pulmonic valve is generally the left second intercostal space. The trachea is a D-shaped fibrocartilaginous respiratory organ. The left branch continues for 5 cm before branching to 2 secondary bronchi. Solution for Nasal cavity Oral cavity O Trachea Esophagus GURE 43.5 Label the features associated with the pharynx. There was no relation of the bifurcation angle to age or gender. The pericardium extends from just superior to the angle of Louis to the level of the xiphisternal joint. Commonly used is the lecithin-sphingomyelin ratio ("L/S ratio"), where a L/S ratio of less than 2:1 means that the fetal lungs may be surfactant deficient, which can result in infant respiratory distress syndrome (IRDS) and ultimately neonatal death. As it descends, the trachea is located anteriorly to the oesophagus, and inclines slightly to the right. Epub 2016 Jun 18. 2022 May;52(3):511-525. Anat Histol Embryol. Now that you've learned everything about the trachea, it's time to put that knowledge to the test with the following quiz! Together, with the capillaries, they form the air-blood barrier. Despite this structure, studies have still shown that immediately after harvesting of the internal mammary artery there can be a period of ischemia affecting the sternum.[10]. Learn the anatomy of all the remaining organs easily and efficiently using Kenhubs respiratory system quizzes and labeled diagrams! It can be palpated easily. The right branch continues behind the ascending aorta for a total length of 2.5 cm before branching to 3 secondary bronchi. Explain the . 3D-measurement of tracheobronchial angles on inspiratory and expiratory chest CT in COPD: respiratory changes and correlation with airflow limitation. government site. We found that the bifurcation of the trachea lay at the plane in 41% of subjects, that the plane passed through the concavity of the arch of the aorta in 49% of subjects, and that, although there was notable individual variation, the manubriosternal plane passed through the upper part of the fifth thoracic vertebra in 53% of cases. The sternal angle is used in the definition of the thoracic plane. In the main bronchi, cartilage rings completely encircle the lumen. Between these two facets, there is an articular disc composed of fibrocartilage. Alavi SM, Keats TE, OBrian WM. This book is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) This website uses cookies to improve your experience while you navigate through the website. Using in-vivo spiral-CT data, the movement in the joint during forced breathing has been measured at approximately 4.4 degrees.[6]. It is roughly at the level of the bifurcation of the trachea. ADVERTISEMENT: Supporters see fewer/no ads, Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Disclaimer. On the right side, the trachea is related to the right, On the left side, the trachea is neighboured by the aortic arch, left recurrent laryngeal nerve, left common carotid artery and left. Normal tracheal bifurcation angle: a reassessment. Access free multiple choice questions on this topic. 2018 Nov;31(11):36-40. (1970) AJR. official website and that any information you provide is encrypted The sternum Q7 Identify structures at the level of the sternal angle. National Library of Medicine There was no relation of the bifurcation angle to age or gender. They undergo further branching to produce the secondary bronchi. The sternal angle is a palpable clinical landmark in surface anatomy. [5], The carina is around the area posterior to where the aortic arch crosses to the left of the trachea. at the level of the manubro-sternal angle of Lois into two primary/principal/main bronchi. Identification of the second rib and thus the second intercostal space inferiorly is also useful when auscultating heart sounds. The trachea, or windpipe, is a 10-11 cm long fibrocartilaginous tube of the lower respiratory tract. The trachea bifurcates and therefore terminates, superior to the heart at the level of the sternal angle. The trachea marks the beginning of the tracheobronchial tree. FOIA Bethesda, MD 20894, Web Policies The tracheal carina is deep to the sternal angle. The https:// ensures that you are connecting to the Pectoralis major has its origin across the anterior surface of the sternum and the sternocostal articulations of the superior ribs, and therefore, includes the sternal angle. Where does the trachea divide. After entering the lungs, the bronchi continue to branch further into the secondary bronchi, known as lobar bronchi, which then branch into tertiary (segmental) bronchi. Unable to load your collection due to an error, Unable to load your delegates due to an error. The carina is a cartilaginous ridge separating the left and right main bronchi that is formed by the inferior-ward and posterior-ward prolongation of the inferior-most tracheal cartilage. The counting of ribs is essential when one is attempting to make a thoracic incision. Each secondary bronchi supplies a lobe of the lung, and gives rise to several segmental bronchi. This article will describe the anatomy and function of the trachea. In addition, there are several lateral relations, as follows: The thoracic part of trachea has several relations as it travels within the superior mediastinum. This site needs JavaScript to work properly. 5. As a result, they cannot maintain the trachea open and it continuously collapses during inspiration and expiration. The trachea, like all of the larger respiratory airways, is held open by cartilage here in C-shaped rings. Reference article, Radiopaedia.org (Accessed on 04 Mar 2023) https://doi.org/10.53347/rID-57629. Please note that some texts differ slightly on certain levels and levels may be altered by patient positioning (supine versus erect) and patient body habitus. It consists of connective tissue that contains mucus glands, smooth muscle, vessels, nerves and lymphatics. These abnormalities often become more pronounced during childhood. In most cases, it ossifies with age. Tracheal bifurcation angle. They reach from the nares and buccal opening to the blind end of the alveolar sacs. The bronchi, the main bifurcation of the trachea, are similar in structure but have complete circular cartilage rings. Clinically Oriented Anatomy (7th ed.). Bifurcation of trachea at sternal angle What are the 3 components of the middle. . The bifurcation can be located anywhere between the levels of the fourth and seventh thoracic vertebrae. Emerg Med Clin North Am. Instead, club cells produce a surfactant lipoprotein which is instrumental in preventing the walls of the small airways sticking together during expiration. All content published on Kenhub is reviewed by medical and anatomy experts. Int J Pediatr Otorhinolaryngol. This joint is also known as the manubriosternal angle (angle of Louis) that serves as an important anatomical landmark. The trachea receives sensory innervation from the recurrent laryngeal nerve. Synonym (s): angulus sterni [TA] , Louis angle, Ludwig angle. The bifurcation is also at a higher level until age 10-12 years. Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. Am J Roentgenol Radium Ther Nucl Med. The trachea is only one part of the respiratory system. In this article we will look at the anatomical position, structure and neurovascular supply of the airways; as well as considering their clinical relevance. The tracheal carina is deep to the sternal angle. Revise with our respiratory system quizzes and labeled diagrams. Mediators Inflamm. The angle decreases by 10 on expiration. Bronchi are plural for bronchus and represent the passageways leading into the lungs. Wang J, Zhou B, Yang X, Zhou C, Ling T, Hu B, Song Y, Liu L. Eur Spine J. It ends at the level of the sternal angle (T5) where it divides into two main bronchi, one for each lung. ISBN:1451119453. It's important because we know that this level marks the level of the intervertebral discs which lies between thoracic vertebra T4 and T5. This article will discuss the anatomy of the bronchi. The most commonly encountered landmarks and structures found at the various vertebral levels are shown in the table below: Medical Exam Prep would like to thank Dr. Marc Barton for permission to reproduce this extract from his book Essential Clinical Surface Anatomy. This information is intended for medical education, and does not create any doctor-patient relationship, and should not be used as a substitute for professional diagnosis and treatment. The tracheal bifurcation angle can have a wide range of normal values in patients and can vary significantly in serial radiographs. [11]It commonly originates from the lower costal cartilages as tendinous fibers and runs superiorly parallel to the sternal body, inserting into the sternal angle. This category only includes cookies that ensures basic functionalities and security features of the website. These bronchi are the widest and they enter the lung. Conducting bronchioles then eventually end as terminal bronchioles. The respiratory portion includes the respiratory bronchiole, alveolar ducts, alveolar sacs, and alveoli. There is remodelling of the small airways, causing increased smooth muscle thickness around the bronchioles, damaged epithelium and a thickened basement membrane. However, there is no definitive evidence of either origin, andsome speculation evensuggests it originates from another doctor, Pierre Charles Alexandre Louis. It arises at the lower border of cricoid cartilage in the neck, as a continuation of the larynx. [1][2][3], Thisangle of Louisis a synarthrosis, a type of joint characterized as a fibrous connection between two bones (the manubrium and the sternal body in the case of the angle of Louis) which does not allow any significant movement. Such diffused involvement happens during Williams-Campbell syndrome. official website and that any information you provide is encrypted Seyfer AE, Shriver CD, Miller TR, Graeber GM. Main bronchi: There are two supplying ventilation to each lung. Theinnermost set of intercostals are thin and are similar to the internal intercostal muscles in their orientation. MeSH Kim Bengochea, Regis University, Denver. 4. After sixth generation, the passageways are too narrow to be supported by the cartillage, and thus are called bronchioles(small bronchi). LWW. The left main bronchus enters the root of the left lung opposite to the sixth thoracic vertebra, passes underneath the aortic arch, and crosses in front of the esophagus, the thoracic duct, and the descending aorta. The manubrium and proximal sternum are routinely opened upduring open-heart surgery. In the standing position trachea bifurcation is at T6 level . Thus, the wide range of normal values is a potential source of misinterpretation 1-3. Learn about the sternal angle in this tutorial. CT assessment of tracheal carinal angle and its determinants. This is the sternal angle. 0. The amount of smooth muscle increases as the amount of cartilage decreases, and smooth muscle is also present continuously around the bronchi. At the time the article was last revised Luke Plant had no recorded disclosures. 164 (5): 1089-92. Alveolar is the final portion of the airway and is lined with a single-cell layer of pneumocytes and in proximity to capillaries. The angle decreases by 10 on expiration. Also, the horizontal plane that passes through the joint and the articular disc between the fourth and fifth thoracic vertebrae divides the mediastinum into superior and inferior parts. These airways are located in the neck and thorax. -, Saran M, Georgakopoulos B, Bordoni B. StatPearls [Internet] StatPearls Publishing; Treasure Island (FL): 2022. As it descends, the trachea is located anteriorly to the oesophagus, and inclines slightly to the right. They are subdivided into different regions with various organs and tissues to perform specific functions. Your email address will not be published. The movement at the sternal angle allows the body of the sternum to move anteriorly and superiorly. Taskin V, Bates MC, Chillag SA. While an angle of tracheal bifurcation greater than 100 may predict left atrial enlargement, this is an insensitive and non-specific sign 4,5. Roberto Grujii MD Asthma is a chronic inflammatory disorder of the airways, characterised by hypersensitivity, reversible outflow obstruction and bronchospasm. Kirum GG, Munabi IG, Kukiriza J, Tumusiime G, Kange M, Ibingira C, Buwembo W. Anatomical variations of the sternal angle and anomalies of adult human sterna from the Galloway osteological collection at Makerere University Anatomy Department. The posterior wall of the trachea is formed by the trachealis muscle, making the cartilages appear as incomplete C-shaped rings. (Sternal angle not labeled, but visible at second, https://en.wikipedia.org/w/index.php?title=Sternal_angle&oldid=1119012903, Creative Commons Attribution-ShareAlike License 3.0, Carina of the trachea is deep to the sternal angle, Passage of the thoracic duct from right to left behind esophagus, Loop of left recurrent laryngeal nerve around aortic arch, This page was last edited on 30 October 2022, at 07:21. Acute bronchitis is often caused by viral or bacterial infections. The structure of its wall makes the trachea sufficiently flexible and elastic to permit the transient expansion of the esophagus during swallowing. Significant pectus excavatum or carinatum is sometimes repaired surgically; these repairs are often performed where the sternal malformation occurs in conjunctionwith significant scoliosis. American journal of roentgenology. The angle of tracheal bifurcation: its normal mensuration. All content published on Kenhub is reviewed by medical and anatomy experts. Unable to process the form. The trachea (windpipe) is found inferior to the thyroid cartilage and superior to division into the left and right main bronchus. These terminal bronchioles branch even further into respiratory bronchioles, which are distinguishable by the presence of alveoli extending from their lumens. To summarize, once the trachea bifurcates into the main left and right bronchus, each bronchus segment is progressively smaller in diameter than the previous segment and subdivides from the segmental bronchus, into the large subsegmental bronchus, into the small subsegmental bronchus, and finally into the bronchioles. Am J Roentgenol Radium Ther Nucl Med. It is located approximately 7 cm below the upper margin of the manubrium. Learning anatomy is a massive undertaking, and we're here to help you pass with flying colours. Segmental bronchi supply individual bronchopulmonary segments of the lungs. This plane passes anteriorly through the sternal angle and posteriorly to the inferior margin of fourth thoracic vertebra. It marks the point at which the costal cartilages of the second rib articulate with the sternum. Author: At the time the article was created Joseph Anderson had no recorded disclosures. However, studies have shown that these repairs do not always lead to improvements in scoliosis and ribcage remodeling. This is particularly useful when counting ribs to identify landmarks as rib one is often impalpable. But opting out of some of these cookies may affect your browsing experience. T1-2 Superior angle of the scapula T2 Jugular notch T3 Base of spine of scapula T4 Sternal angle (of Louis) Division between superior and inferior mediastinum Ascending aorta ends Arch of aorta begins & ends. We also use third-party cookies that help us analyze and understand how you use this website. (1991) Archives of internal medicine. Once thought to be after Antoine Louis or Wilhelm Friedrich von Ludwig, it is now believed to be after Pierre Charles Alexandre Louis.[4]. 1988 Nov;6(4):639-69. 139 (5): 883-7. 0. Kenhub. Vertebral levels (anatomical landmarks). The structure of bronchi are very similar to that of the trachea, though differences are seen in the shape of their cartilage. government site. 1. 2020 Aug;29(8):1981-1992. doi: 10.1007/s00586-020-06383-x. The sternal angle (also known as the angle of Louis, angle of Ludovic or manubriosternal junction) is the synarthrotic joint formed by the articulation of the manubrium and the body of the sternum.[1][2]. [7][8]They later ossify in a craniocaudal direction. Bethesda, MD 20894, Web Policies (1982) AJR. Murray JG, Brown AL, Anagnostou EA, Senior R. Widening of the tracheal bifurcation on chest radiographs: value as a sign of left atrial enlargement. For details about the anatomy of the lungs, take a look at the following: Components that make up the alveolar epithelial lining are: No gas exchange takes place in the bronchi. [4], In a cadaveric study of preserved skeletal specimens, the sternal angle ranged from 149.0 degrees to 177.0 degrees with an average of 163.4 degrees in men and 165.0 degrees in women. Atlas of Human Anatomy (7th ed.). 72. The trachea consists of four histological layers. Sternum, Jugular Notch, Manubrium, Sternal Angle, Body, Xiphoid Process, Clavicular Notch, Facets for Attachment of Costal Cartilages 1-7. The segmental bronchi undergo further branching to form numerous smaller airways the bronchioles. The affected area can span only a few cartilages or affect the entire trachea. Read more. Why is the carina of the trachea so sensitive? Thus, absolute measurements of the tracheal bifurcation angles are of little diagnostic value. JAAPA. All rights reserved. The tracheal bifurcation houses a sagittally-oriented cartilaginous ridge called the carina. The free ends of these rings are supported by the trachealis muscle. [3][4] This is in line with the sternal angle, but the carina may raise or descend up to two vertebrae higher or lower with breathing. This site needs JavaScript to work properly. Every generation, starting from primary, is supported by cartilage in its wall. The angle between the manubrium and the body of the sternum at the manubriosternal junction. Are you curious to find out more about the histology of the lungs? Unable to process the form. The pharynx is the mucous membrane-lined portion of the airway between the base of the skull and the esophagus and is subdivided as follows: Nasopharynx, also known as the rhino-pharynx, post-nasal space, is the muscular tube from the nares, including the posterior nasal cavity, divide from the oropharynx by the palate and lining the skull base superiorly, The oro-pharynx connects the naso and hypopharynx. Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. Is our article missing some key information? A potential pitfall ("Louie's Hot Spot") in bone scan interpretation. Get instant access to this gallery, plus: Introduction to the musculoskeletal system, Nerves, vessels and lymphatics of the abdomen, Nerves, vessels and lymphatics of the pelvis, Infratemporal region and pterygopalatine fossa, Meninges, ventricular system and subarachnoid space. Philadelphia, PA: Lippincott Williams & Wilkins.